The Lipotropic Action of Some Sulfur-con- Taining Amino Acids and Related Substances
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SYNTHESIS AND DETERMINATION OF THE LIPOTROPIC ACTIVITY OF THE BETAINE HYDROCHLORIDES OF dl-SERINE, GTHREONINE, AND dl-ALLOTHREONINE*
This paper reports the synthesis of the betaine hydrochlorides of serine, threonine, and allothreonine and a study of the action of these substances on the lipid content of the livers of rats fed a high fat, low protein diet. This work was undertaken for two purposes. Best and Huntsman (1) found that choline prevented the development of fatty livers in rats fed a high fat diet and that betaine ...
متن کاملSYNTHESIS AND DETERMINATION OF THE LIPOTROPIC ACTIVITY OF THE BETAINE HYDROCHLORIDES OF dl-SERINE, GTHREONINE, AND dl-ALLOTHREONINE*
This paper reports the synthesis of the betaine hydrochlorides of serine, threonine, and allothreonine and a study of the action of these substances on the lipid content of the livers of rats fed a high fat, low protein diet. This work was undertaken for two purposes. Best and Huntsman (1) found that choline prevented the development of fatty livers in rats fed a high fat diet and that betaine ...
متن کاملGrowth and Lipotropism I. the Dietary Requirements of Methionine, Cystine, and Choline by C. R. Treadwell*
Since the reviews by McHenry and Patterson (1) and Best and Lucas (2) on the relationships of lipotropic substances to fat metabolism, several publications have appeared which indicate progress in clarifying the somewhat conflicting views regarding the influence of amino acids and proteins on the fat content of the liver. Beveridge and coworkers (3) have shown that certain essential amino acids...
متن کاملSulfur amino acids in diet-induced fatty liver: a new perspective based on recent findings.
The relationship of sulfur amino acids to diet-induced fatty liver was established 80 years ago, with cystine promoting the condition and methionine preventing it. This relationship has renewed importance today because diet-induced fatty liver is relevant to the current epidemics of obesity, non-alcoholic fatty liver disease, metabolic syndrome, and type 2 diabetes. Two recent papers provide th...
متن کاملThe Lipotropic Action of Threonine and Related Substances in the R,4t* By
With the discovery of threonine through its essentiality in the growth of the rat, it became possible to raise animals on synthetic diets completely devoid of protein (l-3). However, the metabolic fate of this amino acid is still largely unknown today. Its importance in the growth of microorganisms (4) and in the maintenance of nitrogen equilibrium in older animals (5-7) has been demonstrated. ...
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تاریخ انتشار 2003